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Opioid Withdrawal and What To Do

TABLE 4. ACUTE OPIOID WITHDRAWAL SYMPTOMS
SIGN OR SYMPTOM DESCRIPTION NOTES
Pulse rate Elevated pulse rate (above 100 bpm) may indicate withdrawal May also be elevated if participant has been moving about, is feeling anxious, or has consumed caffeine or other stimulants.
Runny nose or tearing Nasal stuffiness, nose running Check if symptoms could be attributed to a cold or allergies before administering opioid antagonist.
Lacrimation Moist and tearing eyes Check if symptoms could be attributed to a cold or allergies before administering opioid antagonist.
Mydriasis Pupils appear larger than normal for room light Observe pupils before administering antagonist to assess for change.
Piloerection Piloerection of skin, or hair standing up on arms Ensure that ambient temperature is not the cause.
Diaphoresis Reports of chills and flushing, observable beads of moisture or sweat Assess for participant activity, room temperature, and other external factors before attributing sweating to opioid withdrawal.
Chills Reports of chills Assess for participant activity, room temperature, and other external factors prior to attributing sweating to opioid withdrawal.
Anxiety or irritability Irritability or anxiousness, observable or self-reported Some participants may have anxiety at baseline, particularly in relation to administration of opioid antagonists. Assess at baseline and question about external cause of anxiety.
Yawning Observed yawning during observation period
Tremulousness Tremors or muscle twitching
GI symptoms Stomach cramps, nausea, loose stools, vomiting, or diarrhea If participant has recently been detoxed from opioids there may be some residual symptoms such as GI discomfort. It is important to assess these symptoms at baseline and monitor for a worsening of these symptoms.